DEP (Transderm Non-Digital)

DEP (DermoElectroPoration® System) is the new Non Invasive, Stand alone powered drug-delivery system carrying Dermoelectroporation® Technology to deliver Ionic drug solution into the body for medical purposes.

As result of more than five years researches, Mattioli Dermoelectroporation® , technology is consolidated to be an incredible procedure that allows the transdermal delivery of whatever substance operators want, which are otherwise not absorbed into the skin because of the typology and dimension of their ownmolecules. Dermoelectroporation® in-fact, increases the skin’s permeability just using some skin’s water based channels opened by a particular controlled current delivered to the-patient and allowing the substances to absorbed till hypo-dermis and muscle membranes.

The system has been FDA approved for the “local administration of ionic drug solutions into the body for medical purposes and can be used as an alternative to injections”.

DEP System is made of the following:

  • Power supply and control base
  • DEP Transdermal delivery handpiece with

DEP System Features:

• Homogeneous drug delivered on the selected area
• Real time control on the amount of drug to delivered
• Real time patient’s skin impedance measurement for successful drug delivery
• Drug administration in a timely manner to avoid waste of product with 100% protection against external agents
• No Electrolysis effect – No drug PH modification
• No need of Pre-charged compounds / Carrying Gels / specific products or particular preparations.

DEP System ensures speed of action, easier regulation of either current delivery and vibration and monitors skin impedance on real time to give users the final results they expect. The new revolutionary handpiece allows users to see and manage at best the delivery with no waste of product and getting optimal results.

Operators will enjoy the accuracy provided by the DEP System handpiece for any skin condition and for any length of treatment.

Patients will enjoy treatments with DEP System due to the very high comfortable sessions. Vibration feature makes electrical pulses delivery perception to decrease significantly and the handpiece won’t allow undesired spilling of product.

Macromolecules (such as Hyaluronic Acid) previously not transdermally deliverable by traditional Ionthophoresis are now successfully deliverable due to the new Dermoelectroporation® Technology.


  • Easy to use
  • FDA cleared as alternative to injections.
  • New Internationally Patented proprietary Dermoelectroporation® Technology.
  • Non invasive.
  • Current delivery perception protected.
  • Control on homogeneous drug delivery.
  • 100% drug protection against external agents.
  • Real time skin impedance measurement feature.
  • Real time transdermal delivery monitoring.
  • Control on either amount of drug to be delivered and time of treatment.
  • Capability of Transdermal Delivery of ionic drug solution of macromolecules (greater than 800.000 Dalton!).

Some applications:

  • Hyperhidrosys
  • Skin Rejuvenation treatments
  • Wrinkles treatments
  • Pre laser treatments
  • Pre and post plastic surgery sessions
  • Skin Whitening treatments
  • Steroids applications
  • Aesthetic applications
  • Replacing injections for Mesotherapy applications and many others

Some deliverable drugs:

  • Type A Botulinum Toxine
  • Phosphatidylcoline
  • Hyaluronic Acid
  • Aminophylline
  • Grow Factors
  • Amino Acids
  • L-Carnitine
  • Lidocaine
  • Heparine
  • Collagen
  • Vitamins
  • Steroids
  • Elastine and many others

Benefit to patients:

  • Astonishing results
  • Comfortable treatment sessions
  • No irritations, burnings or inflammations for return electrode placement
  • No trauma from injections

For more information on our DEP (Transderm Non-Digital), don’t hesitate to contact us on 01234 841536.

Interest free credit available on all purchases during October, call us on 01234 841536 to find out more